Mass Avenue is a major thoroughfare and a center of commercial activity with heavy pedestrian traffic. It crosses many major streets of Boston including Boylston St., Commonwealth Ave., Huntington Ave., Newbury St., Storrow Drive, and Tremont St.. World class universities such as Harvard University, MIT, and Berklee College of Music can be found here. Religious and cultural points of interest such as the Christian Science Center and Symphony Hall are here as well as Harvard Square with it's eclectic and cultural vibe where you will find a diverse range of shops, restaurants, pubs, coffee-houses and popular university hang-outs.

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The Boston and Cambridge Stretch: Symphony Hall, Christian Science Center, MIT, Berklee College of Music, Harvard University, Cambridge City Hall, Arlington Town Hall, Lexington Battle Green. It's length spans numerous towns and cities from Lexington to Dorchester crossing many town centers.